Episode 5 in a 6-part mini documentary series, see the full series here: http://www.lifetechnologies.com/exosomesdocumentary
We asked 10 prominent scientists to share their thoughts on science and in particular the field of exosomes research. The video-series tell the story and history of this exciting new area of research, and its impact on other research fields such as cancer and immunology. The video-series also discusses the potential future therapeutic and diagnostic applications that may come from exosome research.
- Xandra Breakefield, Ph.D........... Professor, Massachusetts General Hospital
- Jan Lötvall, MD., Ph.D .............. Professor, University of Gothenburg, President of ISEV
- Suresh Mohla, Ph.D.................. Chief (TBMB) and Division Associate Director, NIH
- Esther Nolte-'t Hoen, Ph.D......... Senior Scientist, Utrecht University
- Michiel Pegtel, Ph.D................. Assistant Professor, VUmc, Amsterdam
- Graça Raposo-Benedetti, Ph.D.. Director of Research, CNRS, Institut Curie
- Phillip A. Sharp, Ph.D............... Nobel Laureate, Professor, MIT
- Johan Skog, Ph.D.................... CSO, Exosomes Diagnostics
- Dima Ter-Ovanesyan.................Ph.D Student, Harvard University
- Clotilde Thery, Ph.D................. Director of Research, INSERM, Institut Curie, Secretary General of ISEV
Members of the research groups of Michiel Pegtel (Cancer Center Amsterdam, VUmc), Graça Raposo-Benedetti (Structure and Membrane Compartments, CNRS, Institut Curie) and Clotilde Théry (Immunity and Cancer, INSERM, Institut Curie)
Special thanks to the ISEV society for their strong contribution in leading the field of exosome research forward, and to the participants at the ISEV RNA Workshop in New York City October 1st-2nd 2012
Kudos to all scientists that have the courage to follow their curiosity!
If you want to learn about the exosomes-specific products available from Life Technologies: http://www.lifetechnologies.com/us/en/home/life-science/cell-analysis/exosomes.html?cid=exoep5
This site provides links to random videos hosted at YouTube, with the emphasis on random.
The original idea for this site actually stemmed from another idea to provide a way of benchmarking the popularity of a video against the general population of YouTube videos. There are probably sites that do this by now, but there wasn’t when we started out. Anyway, in order to figure out how popular any one video is, you need a pretty large sample of videos to rank it against. The challenge is that the sample needs to be very random in order to properly rank a video and YouTube doesn’t appear to provide a way to obtain large numbers of random video IDs.
Even if you search on YouTube for a random string, the set of results that will be returned will still be based on popularity, so if you’re using this approach to build up your sample, you’re already in trouble. It turns out there is a multitude of ways in which the YouTube search function makes it very difficult to retrieve truly random results.
So how can we provide truly random links to YouTube videos? It turns out that the YouTube programming interface (API) provides additional functions that allow the discovery of videos which, with the right approach, are much more random. Using a number of tricks, combined some subtle manipulation of the space-time fabric, we have managed to create a process that yields something very close to 100% random links to YouTube videos.
YouTube is an American video-sharing website headquartered in San Bruno, California. YouTube allows users to upload, view, rate, share, add to playlists, report, comment on videos, and subscribe to other users. It offers a wide variety of user-generated and corporate media videos. Available content includes video clips, TV show clips, music videos, short and documentary films, audio recordings, movie trailers, live streams, and other content such as video blogging, short original videos, and educational videos. Most content on YouTube is uploaded by individuals, but media corporations including CBS, the BBC, Vevo, and Hulu offer some of their material via YouTube as part of the YouTube partnership program. Unregistered users can only watch videos on the site, while registered users are permitted to upload an unlimited number of videos and add comments to videos. Videos deemed potentially inappropriate are available only to registered users affirming themselves to be at least 18 years old.
YouTube and selected creators earn advertising revenue from Google AdSense, a program which targets ads according to site content and audience. The vast majority of its videos are free to view, but there are exceptions, including subscription-based premium channels, film rentals, as well as YouTube Music and YouTube Premium, subscription services respectively offering premium and ad-free music streaming, and ad-free access to all content, including exclusive content commissioned from notable personalities. As of February 2017, there were more than 400 hours of content uploaded to YouTube each minute, and one billion hours of content being watched on YouTube every day. As of August 2018, the website is ranked as the second-most popular site in the world, according to Alexa Internet, just behind Google. As of May 2019, more than 500 hours of video content are uploaded to YouTube every minute.
YouTube has faced criticism over aspects of its operations, including its handling of copyrighted content contained within uploaded videos, its recommendation algorithms perpetuating videos that promote conspiracy theories and falsehoods, hosting videos ostensibly targeting children but containing violent and/or sexually suggestive content involving popular characters, videos of minors attracting pedophilic activities in their comment sections, and fluctuating policies on the types of content that is eligible to be monetized with advertising.